Pharmacology

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Correct Answer - D Ans. is 'd' i.e., Shows cross reactivity with other penicillins Aztreonam It belongs to monobactams group of 13-lactam antibiotics. It is active against gram negative organisms including pseudomonas, but has no activity against gram positive organisms or anaerobes fi-lactam antibiotic with aminoglycosides spectrum. It is the only fi-lactam antibiotic that lack cross-reactivity with other P-lactam antibiotics, permiting its used in patients allergic to penicillins or cephalosporins. @pharma_vid

Correct Answer - B Answer: B - Neuro-endopeptidase inhibitor Sacubitril,a prodrug inhibiting neuro-endopeptidase enzyme Activated to Sacubitril, Inhibiting enzyme neprilysin (Neutral endopeptidases) Combination drug used in heart failure patients Usually combined with ACE inhibitors like valsartan in ratio of 1:1 @pharma_vid