Dermatology

Diffuse melanosis cutis is a rare presentation of metastatic melanoma. In this condition, the entire colour of the surface of the skin changes. Approximately 1 to 2 percent of patients with metastatic melanoma are affected with melanosis cutis. Although, the exact pathophysiology of the underlying diffuse melanosis is unknown. A theory suggests that it may be caused because of circulating melanin precursors released by melanoma cells. The melanoma cells enter the dermis and undergo auto-oxidisation to melanin with dermal extracellular fluid and dermal histiocytes. Melanosis cutis presents with clinical features including a progressive blue-gray discolouration of the entire skin and mucous membrane. The discolouration typically occurs over the time span of weeks or months. It is also associated with darkening of urine, malanuria which becomes more pronounced as the urine stands. https://www.facebook.com/groups/207249543351286/permalink/1664577897618436/

A 59-year-old veterinarian presented to the dermatology clinic with a 1-year history of a painful rash on his right hand. He had no other symptoms. On physical examination, verrucous plaques with overlying thick yellow-brown crusting were seen on the dorsum of the right hand (Panel A) and the medial aspect of the right index finger (Panel B). Biopsy of the lesion on the dorsum of the hand revealed pseudoepitheliomatous hyperplasia and tuberculoid granulomas in the dermis (Panel C, arrow; hematoxylin and eosin stain). Tissue cultures were negative, but metagenomic next-generation sequencing of the tissue identified Mycobacterium tuberculosis. An interferon-γ release assay was positive, and a computed tomographic scan of the chest was normal. A diagnosis of tuberculosis verrucosa cutis was made.

Cutaneous myiasis occurs on exposed skin,often the face, scalp, arms or legs. In the furuncular form, boil-like lesions develop gradually over a few days. Each lesion has a central punctum, which discharges sero-sanguinous fluid. The posterior end of the larva, equipped with a group of spiracles, is usually visible in the punctum. The lesions are often extremely painful. Lymphangitis, regional lymphadenopathy, systemic symptoms or secondary  bacterial infection may occur. Lesions rapidly resolve once the larva emerges/is removed. Some larvae can be expressed by firm pressure around the edges of the lesion. Others require surgical management. Ivermectin isused if surgery is unsuccessful. Infected wounds require surgical debridement andirrigation to remove larvae, plus treatment ofsecondary infection. د. ياسر الهبيط أخصائي الأمراض الجلدية والتناسلية والتجميل https://www.facebook.com/100024027590297/posts/

بالضبط 👌🏻 . وما أكثرهم في : 🫥الجلدية والتناسلية 🫥 ، والتجميل 🫥 .

Case of impetigo https://www.facebook.com/100024027590297/posts/

Bolognia 5th Edition 2024 - Small sized pdf

Urticaria + Psoriasis https://www.facebook.com/100024027590297/posts/